Short answer
Remove solids, blot (don't rub) with paper towels, and keep added water to a minimum. Drool and vomit are organic matter, so the odor comes from residue in the fabric, which is what enzyme treatment targets. Pet odor treatment is included in our mattress price, along with normal stains.
Book your mattress cleaning
Regular price $249, Fall 2026 promotion price $199first mattress, any size · Fall 2026 promotion
HEPA vacuuming, enzyme treatment for organic odor, dry vapor steam and UV-C. We recommend cleaning twice a year.
Right away
- Lift off solids with a paper towel or spatula. Don't press them in.
- Blot with dry paper towels until nothing more transfers.
- Don't flood it. Pouring water or cleaner on the spot pushes residue deeper (where water goes in a mattress).
- Skip the fragrance. Scented sprays cover the smell without removing the residue (fragrance masking vs odor removal).
Why the smell lingers
Drool leaves saliva and oils in the fabric, and vomit leaves food and stomach contents. Both are organic residue, and residue is what holds odor. Enzyme treatment is made to break down organic residue (enzymes vs fragrance).
How we treat it
Inspection to find where the residue sits, HEPA vacuuming, enzyme treatment on the spot, low-moisture dry vapor steam and UV-C. Pet odor and normal stain treatment are included. For urine, see the pet urine and accidents hub.
Where to read next
How we clean a bed you share with a pet
This section is our view. Every Sleep Sanitation visit starts with a nose-and-eyes inspection, then HEPA vacuuming to lift hair, dander and debris, enzyme treatment on organic odor, low-moisture dry vapor steam from our Italian-made Vapor Clean machines, UV-C light treatment and a moisture check before we leave. Pet odor treatment is included in the mattress price, along with normal stains and ordinary urine accidents. The first mattress is $199 Fall 2026 special (regularly $249), any size, and underside treatment is +$50–$75. We recommend cleaning every mattress twice a year, and more often is fine when a pet shares the bed. Take the 60-second mattress quiz or schedule your cleaning. Call or text (402) 512-5658, or email info@sleepsanitation.com.
Changelog
- 24 October 2026: First published. Sources accessed on this date.
Sources
Last reviewed October 24, 2026. Manufacturer specifications and care instructions change; check the current version for your exact model. This page is general information, not medical advice. How we source and check pages: editorial standards.