Short answer
Not unless the manufacturer says the cover is removable. Some mattresses use a fire barrier that contains glass fiber under the cover, and removing it can expose that layer. Check the law tag and care label first. If it says spot clean only, leave it on and clean it in place.
Book your mattress cleaning
Regular price $249, Fall 2026 promotion price $199first mattress, any size · Fall 2026 promotion
HEPA vacuuming, enzyme treatment for organic odor, dry vapor steam and UV-C. We recommend cleaning twice a year.
Why the zipper is there
On many mattresses the zipper is a manufacturing feature. The cover may hold the layers together, and under it there may be a fire barrier. Some barriers use glass fiber (fire barriers and fiberglass).
Check first
- Law tag and care label. Look for "do not remove cover" or "spot clean only" (how to read a law tag).
- The maker's site. Tempur-Pedic, for example, lists which of its covers are removable and which are spot clean only (Tempur-Pedic).
The no-unzip way to clean it
Vacuum, spot clean lightly and use a protector. For a deeper clean we treat the cover in place: HEPA vacuuming, enzyme treatment, low-moisture dry vapor steam and UV-C, with nothing unzipped.
Where to read next
Every type, one low-moisture method
This section is our view. Memory foam, latex, hybrid and pillow-top mattresses all share one rule: keep water out of the core. Every Sleep Sanitation visit starts with a check of your care label and an inspection, then HEPA vacuuming, enzyme treatment on organic stains and odor, low-moisture dry vapor steam from our Italian-made Vapor Clean machines, UV-C light treatment and a moisture check before we leave. Stains, normal accidents and pet odor are included. The first mattress is $199 Fall 2026 special (regularly $249), any size. Each additional king is $199, each full or queen is $179, and underside treatment is +$50–$75. We recommend cleaning every mattress twice a year. Take the 60-second mattress quiz or schedule your cleaning. Call or text (402) 512-5658, or email info@sleepsanitation.com.
Changelog
- 24 October 2026: First published. Sources accessed on this date.
Sources
- Can I clean the cover of my mattress? · Tempur-Pedic
Last reviewed October 24, 2026. Manufacturer specifications and care instructions change; check the current version for your exact model. This page is general information, not medical advice. How we source and check pages: editorial standards.